Bio-Materials and Prototyping Applications in Medicine by Paulo Jorge Bártolo, Bopaya Bidanda

By Paulo Jorge Bártolo, Bopaya Bidanda

Bio-materials and prototyping (both digital and actual) is turning into an increasing number of established in medication. those fabrics and applied sciences are used to layout, boost and manufacture scientific units and instrumentation, and to manufacture drug dosage kinds. This approach is usually more and more getting used by way of surgeons to plot complicated operations, specifically within the craniofacial and maxillofacial components. additional, prototyping exhibits promise within the quarter of tissue engineering by utilizing biomaterials together with the direct manufacture of biologically lively implants. This ebook specializes in bio fabrics and prototyping functions in scientific environments. The purposes which are mentioned combine bio-materials, CAD, and actual prototyping techniques.

Summarizes cutting-edge examine in prototyping of bio-materials for scientific applications

Provides a large choice of examples of scientific functions utilizing fast prototyping, together with tissue engineering, dental purposes, and bone replacement

Addresses the problems concerned with utilizing good freeform fabrication/rapid prototyping/layered production that's turning into extremely important within the biomaterials area

Discusses the emergence of machine aided layout within the improvement of prosthetic devices

 

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Extra resources for Bio-Materials and Prototyping Applications in Medicine

Sample text

This material was particularly chosen because it reduced the problem of ‘‘capsular contracture’’, a common complication in breast augmentation surgery where tissue forming around the implant 42 F. J. Davis, G. R. Mitchell contracts and causes the implant to appear hardened (Handel and Gutierrez, 2006). It was found that on removal of the implants substantial amounts of the polyurethane material was missing (Slade 1982) this led to concerns that the degradation of the polyurethane in these materials could release substantial amounts of toluene diisocyanate, a potential carcinogen.

1998). In the following discussion we shall focus on the behaviour of elastomeric materials as it is these, which dominate the market in terms of medical devices. The principal feature of polyurethane elastomers is the phase segmentation of the hard and soft segments (Kro´l, 2007). Strictly the polymer shown in Fig. 3 is a block copolymer of a polyether urethane and a polyurea, as shown in Fig. 5. As with other block copolymers it is the possibility of micro phase segregation, which makes these materials particularly interesting.

J Biomed Mater Res 69A:407–416 Christenson EM, Patel S, Anderson JM, Hiltner A (2006) Enzymatic degradation of poly(ether urethane) and poly(carbonate urethane) by cholesterol esterase. Biomaterials 27:3920–3926 Courtney T, Sacks MS, Stankus J, Guan J, Wagner WR (2006) Design and analysis of tissue engineering scaffolds that mimic soft tissue mechanical anisotropy. Biomaterials 27:3631–3638 Demir MM, Yilgor I, Yilgor E, Erman B (2002) Electrospinning of Polyurethane Fibres. Polymer 43:3303–3309 Ellison CJ, Phatak A, Giles DW, Macoskoa CW, Bates FS (2007) Melt blown nanofibers: fiber diameter distributions and onset of fiber breakup.

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