An Atlas of Pathology of the Brain by E.E Payne

By E.E Payne

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Second-order neurons lie within the deeper layers of the posterior horn and give rise to axons that decussate in the ventral white commissure just anterior to the central spinal canal, converging within the lateral funiculus to form the spinothalamic tract. Secondorder neurons ascend contralaterally within the anterolateral funiculus to synapse within the VPL nucleus of the thalamus and within the posterior interlaminar nuclei of the thalamus. Third-order neurons arise within the VPL of the thalamus and project through the posterior limb of the internal capsule arriving at the primary somatosensory cortex (Brodman’s area 1, 2, and 3).

7 Anatomical changes over the length of the spine demonstrated in select axial sections. M. ) of mechanoreceptive kinesthesia for the modulation of fine motor control and posture. Although this sensory information is crucial to normal joint and muscle action, their isolated functions cannot be clinically localized very easily unless the larger tracts are compromised. Ascending pathways include the dorsal and ventral spinocerebellar, spino-olivary, spinotectal, spinoreticular, spinocervical, and spinovestibular tracts.

First-order neuron cell bodies are located within the dorsal root ganglia at all spinal levels. First-order axons enter the spinal cord along the dorsolateral tract of Lissauer (lateral root entry zone) at the posterior horn and synapse with second-order neurons. Second-order neurons lie within the deeper layers of the posterior horn and give rise to axons that decussate in the ventral white commissure just anterior to the central spinal canal, converging within the lateral funiculus to form the spinothalamic tract.

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